research-highlights

Engineering Synthetic Apomixis to Enable Clonal Hybrid Seed Production in Sorghum

Synthetic apomixis was successfully engineered in hybrid sorghum, enabling clonal seed formation that preserves hybrid heterozygosity across generations, although further optimization is needed to improve fertility and developmental stability.

Integrated Morphological, Physiological, and Transcriptional Mechanisms Underlying Waterlogging Tolerance in Sorghum

The sorghum genotype ‘S208’ exhibits superior waterlogging tolerance through coordinated activation of anaerobic energy metabolism, hormone signaling, and cell wall remodeling that drives adventitious root formation and aerenchyma development under hypoxic conditions.

Rp2: A Novel Rust Resistance Locus from Sudanese Sorghum for Broadening Genetic Diversity in U.S. Breeding Programs

Evaluation of the Sudan core collection of tropical sorghum germplasm identified rare accessions with dual resistance to rust and anthracnose and revealed the novel Rp2 NBS–LRR resistance locus, highlighting an underutilized genetic resource for introgressing durable disease resistance and expanding the genetic diversity of U.S. sorghum breeding programs.

WRKY76-miR528-SOD2 Regulatory Module Governs Submergence Tolerance in Sorghum

Sorghum submergence tolerance is governed by a WRKY76–miR528–SOD2 regulatory module that controls oxidative stress responses, revealing key molecular targets for improving crop resilience to flooding.

SbHMA5-Mediated Copper Efflux and Metallochaperone Interactions Regulate Copper Homeostasis in Sorghum

SbHMA5 is a conserved P1B-type copper ATPase in sorghum that maintains copper homeostasis by interacting with metallochaperones to efflux excess Cu from the cytosol, thereby protecting plant growth and development from copper toxicity.

Evolutionary, Structural, and Functional Diversification of Polyamine Oxidase Genes Underlying Drought Tolerance in Sorghum

Sorghum polyamine oxidase genes exhibit distinct structural, evolutionary, and regulatory specializations that shape tissue- and genotype-specific stress responses, with SbPAO5 and SbPAO6 emerging as key contributors to drought tolerance and promising targets for crop improvement.

Integrated Cytological and Multi-Omics Analysis Reveals Phenylpropanoid-Mediated Regulation of Leaf Angle Formation in Sorghum

Leaf angle formation in sorghum is driven by coordinated changes in auricle cell development, phenylpropanoid-mediated lignin biosynthesis, and associated gene expression, collectively shaping plant architecture for improved light capture.

Stem-Preferred Gene Regulation and Meristematic Origins Underlying Transcriptional Specificity in Sorghum

A genome-wide analysis of sorghum revealed that stems possess relatively few organ-specific genes due to their meristematic origins, with two KNOX-like transcription factors, SbTALE03 and SbTALE04, emerging as key stem-preferred regulators and promising tools for targeted engineering supported by regulatory and network evidence.

Integrative Molecular and Physiological Mechanisms Underlying Drought Tolerance in Sorghum

Drought tolerance in sorghum arises from coordinated molecular, biochemical, and physiological mechanisms, including elevated osmoprotectant levels, enhanced antioxidant defenses, and activation of ABA-dependent bZIP transcription factors that collectively maintain cellular stability and promote resilience under water stress.