news & research-highlights

CSHL Tutorials in Genomics & Bioinformatics: RNA-Seq Analysis course, May 10-12

The Tutorials in Genomics & Bioinformatics: RNA-Seq (TGB) course is a two-day, immersive introduction to genomics and bioinformatics, designed to equip researchers with the conceptual foundation and practical skills needed to analyze high-throughput sequencing data. Modeled after Cold Spring Harbor Laboratory’s renowned Genome Access Course, TGB emphasizes active learning, real data analysis, and direct engagement with expert instructors.

Co-Regulatory Networks Underlying Protein and Starch Biosynthesis and Digestibility in Developing Sorghum Grain

Integrated transcriptomic–biochemical network analysis of developing sorghum grain identified interconnected regulatory modules for protein and starch biosynthesis, highlighting SbPBF1a, SbPBF1b, and SbNF-YC13 as candidate central transcriptional regulators and revealing structural genes potentially underlying low protein digestibility.

CSI Seminar Ethan Triplett, Apr 14 at 11 AM CT

The Center for Sorghum Improvement (CSI) will host a virtual seminar by Dr. Ethan Triplett, Director of Crop Improvement for the United Sorghum Checkoff Program, National Sorghum Producers, on Tuesday, April 14 at 11:00 AM CT. His talk, titled “Translation,

Heritable Genetic Architecture of Dynamic Photoprotection and NPQ Kinetics in Field-Grown Sorghum

Field evaluation of a large sorghum diversity panel revealed heritable, environmentally responsive variation in NPQ capacity and kinetics, and integrative genomic analyses identified polygenic candidate loci—many linked to redox regulation, stress signaling, and photosynthetic control—that provide targets for improving photoprotection and photosynthetic efficiency in C4 crops.

Phytohormone Dynamics Underlying Reproductive Cold Tolerance in Sorghum

Reproductive cold tolerance in sorghum is primarily associated with tight abscisic acid homeostasis—rather than gibberellin limitation or jasmonate induction—and appears to affect yield through mechanisms beyond pollen fertility, likely involving female reproductive processes.

Conserved and Dynamic Gene Regulatory Networks Underlying Nitrogen Use Efficiency in Cereal Crops

Conserved gene regulatory networks underpin nitrogen metabolism across plants, with dynamic and species-specific rewiring in maize and sorghum during rapid nitrogen deprivation and recovery, revealing key transcriptional regulators that shape nitrogen use efficiency and sustainable crop productivity.

Advancing Sorghum Genomics: Design and Application of the Twist 100K Genotyping Array

SorghumBase invites the global sorghum research and breeding community to join an upcoming webinar taking place March 31st on the design and implementation of the Twist 100K genotyping array, a next-generation resource developed through broad community engagement and cutting-edge genomic approaches.

Heme-Dependent Dimerization and ER Membrane Remodeling by the Sorghum Membrane Steroid Binding Protein SbMSBP1

SbMSBP1 is an ER-localized MAPR protein in sorghum that binds heme, undergoes heme-dependent dimerization, and promotes membrane remodeling, suggesting roles in vesicle trafficking, cytochrome P450 stabilization, and stress-adaptive specialized metabolism.

Single Cell & Spatial Transcriptomics Analysis course Will Be Held Jun 25- Jul 13, 2026 at CSHL, Applications Due Mar 27

Cold Spring Harbor Laboratory is hosting the Single Cell & Spatial Transcriptomics Analysis course, June 25-July 13. This intensive two-week course trains students in state-of-the-art wet-lab methods for single-cell analysis and builds foundational skills in bioinformatic handling of single-cell data.