Weighted gene co-expression network analysis - based selection of hub genes related to phenolic and volatile compounds and seed coat color in sorghum.

Lee YJ, Kim WJ, Lee SH, Kim JH, Kwon SJ, Ahn JW, Kim SH, Kim JB, Lyu JI, Bae CH, Ryu J

Published: 23 May 2025 in BMC plant biology
Keywords: Network analysis, Phenolics, R-seq, Seed coat color, Sorghum, Volatile compound
Pubmed ID: 40410657
DOI: 10.1186/s12870-025-06657-w

BACKGROUND: Sorghum grains are rich in phenolic compounds, which are noted for their anticancer, antioxidant, and anti-inflammatory properties, as well as volatile compounds (VOCs) that contribute to aroma and fermentation processes. There is a known close relationship between sorghum coat color and phenolic compound content (PCC), particularly flavonoids which are pigments that confer red and purple colors in flowers and seeds.RESULTS: Our results showed that black seeds had the highest total tannin content (TTC) and ketone content, which were measured at 457.7 mg CE g-1 and 96 g 100 g-1, respectively, which were 4.87 and 1.35 - fold higher than those of white seeds. L* showed a negative correlation between TTC (r = -0.770, P 

Korea Atomic Energy Research Institute - research program 523410-24
Republic of Korea government - National Research Foundation of the Republic of Korea (NRF) RS-2022-00156231