BACKGROUND: Wheat and, to a lesser extent, sorghum are the dominant feed grains in Australian chicken-meat production. There is considerable local interest in the development of reduced-crude protein (CP) broiler diets in part because this would decrease the need to import soybean meal into the country. Maize is rarely included in Australian broiler diets, but birds appear better able to accommodate dietary CP reductions with maize than with wheat-based diets. Sorghum is more similar to maize than wheat and for this reason wheat- and sorghum-based diets, with standard and reduced-CP concentrations, were evaluated in broiler chickens in a direct comparison.RESULTS: Reducing dietary CP from 205 to 175 g/kg CP did not statistically influence weight gain and FCR in broilers offered sorghum-based diets from 14 to 35 d post-hatch. In contrast, the 30 g/kg CP reduction compromised weight gain by 10.1% (1,964 versus 2,187 g/bird) and FCR by 9.68% (1.575 versus 1.436), in broilers offered wheat-based diets. Consequently, treatment interactions (P